DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
نویسندگان
چکیده
منابع مشابه
Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes.
Wilms tumor (WT) is the most common childhood renal cancer. Recent findings of mutations in microRNA (miRNA) processing proteins suggest a pivotal role of miRNAs in WT genesis. We performed miRNA expression profiling of 36 WTs of different subtypes and four normal kidney tissues using microarrays. Additionally, we determined the gene expression profile of 28 of these tumors to identify potentia...
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Purpose Medulloblastoma (MB), the most common malignant brain tumor in children, is divided into four tumor subgroups: wingless-type (WNT), sonic hedgehog (SHH), Group 3, and Group 4. Ideally, clinical practice and treatment design should be subgroup specific. While WNT and SHH subgroups have well-defined biomarkers, distinguishing Group 3 from Group 4 is not straightforward. MicroRNAs (miRNAs)...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2011
ISSN: 1523-5866,1522-8517
DOI: 10.1093/neuonc/noq190